Charles C. Tseng, Ph.D.

Office: Gyte 291
Telephone: (219) 989-2403
Email: tseng@calumet.purdue.edu

Education

B.S. Biology, Taiwan Normal University, Taipei, Taiwan
M.S. Botany, National Taiwan University, Taipei, Taiwan
Ph.D. Botany, University of California, Los Angeles, California

Research

     Dr. Tseng's research is in the field of DNA technology. Current research projects include 1) the effect of radiofrequency fields on human and bacterial gene expression, 2) development of a high resolution genome scan technology for identifying the genomic variations of E. coli and C. elegans, and 3) development of DNA vaccines for infectious diseases and cancer.

3 grants for the Department of Defense Air Force MURI Program ($2.65 million, 2002-7),
1 grant from The Institute of Genomics Research (TIGR) ($75,000, 2005-),
1 grant from Oakland, CA ($3,500, 2005-6),
1 grant from Indiana USGS ($2,450, 2003-4),
2 grants from Oklahoma USGS ($30,000, 2002-4),
1 grant from National Oceanic and Atmospheric Administration (NOAA) ($150,000, 2001-3),
1 grant from Illinois Lake County Department of Health ($26,000, 2002-3)
5 grants from Illinois-Indiana Sea Grant Program ($222,000, 1995-2002)
1 grant from National Science Foundation (NSF) ($32,000, 1994-97).

Most Recent Publications and Invited Talks (2005-2006)

Refereed Journal Publications

• Byappanahalli MN, RL Whitman, DA Shively, WT Ting, CC Tseng, and MB Nevers (2006) Seasonal persistence and population characteristics of Escherichia coli and enterococci in deep backshore sand of two freshwater beaches. J. Water and Health. 4:313-32o
• Gerber, HL, A Bassi, MH Khalid, CQ Zhou, SM Wang, and CC Tseng (2006) Analytical and experimental dosimetry of a cell culture in T-25 flask housed in a thermally controlled waveguide.   IEEE Transactions on Plasma Science 34:1449-1454
• Gerber, HL, A Bassi, and CC Tseng (2006) Determining a pulse coupling to subcellular components with a frequency-domain transfer function.  IEEE Transactions on Plasma Science 34: 1425-1430
• Lee S, D Johnson, K Dunbar, H Dong, X Ge, YC Kim, C Wing, N Jayathilaka, N Emmanue, CQ Zhou, HL Gerber, CC Tseng, SM Wang (2005) 2.45 GHz Radiofrequency fields alter gene expression in cultured human cells. Federation of European Biological Society Letters 579:4829-4836
• Lee S, J Bao, G Zhou, J Shapino, J Xu, RZ Shi, X Lu, T Clark, D Johnson, YC Kim, C Wing, C Tseng, M Sun, W Lin, J Wang, W Du, C-I Wu, X Zhang, SM Wang (2005) Detecting novel low-abundant transcripts in Drosophila. RNA 11(6):939-946
   
  Publications in Refereed Conference Proceedings

• Khalid M, C Zhou, A Bassi, SM Wang, H Gerber, C Tseng (2005)  Heat  transfer analysis of human cell culture under RF exposure. Proceedings of 2005 ASME Summer Heat Transfer Conference, July 17 – 22, 2005, San Francisco, CA, 9 pages

Published Abstracts

• Tseng CC (2006) A New Genome Scan Technology for E. coli Source Tracking,  National Beach Conference. In press
• Zhang X, X Hong, G Chen, SM Wang, KH Schoenbach, CQ Zhou, HL Gerber, and CC Tseng (2006) Nanosecond pulsed electric fields enhance IL-2 expression in Jurkat cells. BEMS 2006 Abstract PB-126:1-2 
• Wang Z-M, X Ge, SM Wang, A Bassi, M Khalid, KH. Schoenbach, CQ Zhou, HL Gerber, and  CC Tseng (2006) Effect of nanosecond pulsed electric fields: early response genes for DNA damage repair and cell cycle arrest. BEMS 2006 S4-1:1-2
• Gealt MA, Z-M Wang, DS Johnson, P Smutko, J Spyridakis, K Schoenbach, and CC Tseng        (2006) Escherichia coli Induces specific  repair genes in response  to nsPEF. BEMS 2006 S4-8:1-2
• Gerber HL, S Li, and CC Tseng (2006) Electrical transfer functions associated with normal and malignant white cells. BEMS 2006 PA-125:1-2
• Khalid M, A Bassi, HL Gerber, CC Tseng, and Chenn Q. Zhou (2006) Analysis of cell  distribution in a culture medium within a RF exposure system. BEMS 2006 PA-127:1
• Khalid M,  C Zhou,  A Bassi, H Gerber,  C Tseng, Q Wan, N Xu (2005) Heat Transfer Analysis of a Human Cell Culture In a Micro nsPEF System. ElectroMed2005 Symp.  p.12
• Wang ZM, Ge X, D Zho, A Bassi, M Khalid, CQ Zhou, K Schoenbach, HL Gerber, CC Tseng (2005) Genomic responses of Jurkat cells to nanosecond pulsed electric fields. ElectroMed2005 Symp. p. 13-14
• Gerber HL, A Bassi, M Khalid, CQ Zhou, CC Tseng (2005) Determining   pulse coupling to sub-cellular component with a frequency domain transfer function. ElectroMed2005 Symp. p.15
• Wang ZM, C Tseng, D Johnson, J Spyridakis, P Smutko, W Xie, M Gealt (2005) Escherichia coli Responds to  nsPEP with  induction  of DNA repair  functions.  ElectroMed2005 Symp. p.18-19
• Dong H, X Ge, Y C. Kim, S Lee, HL Gerber, CQ. Zhou, CC Tseng, SM Wang (2005) Determine the Identity of 2.45 GHz RF Response Genes. ElectroMed2005 Symp. p.  84-85
• Gerber HL, A Bassi, M Khalid, CQ Zhou,  CC Tseng (2005) Analytical and experimental dosimetry of a 10 ml cell suspension in a  thermally-controlled waveguide. ElectroMed2005 Symp. p. 86-88
• Tseng CC, MA Gealt, SM Wang (2005) Genomic responses to RF fields: Current research of AFOSR Purdue MURI Consortium. BEMS 2005, p. 161-163
• Gealt MA, SM Wang, CC Tseng (2005) E. coli responds to nsPEP with induction of DNA repair  functions. BEMS 2005, p. 165-166
• Wing C, P Frohnapple, Y-M Chun, CC Tseng, YD Choi (2005) Asian lineage of the new subspecies of common reed (Phrogamites australis subsp. americanus Seltonstall, P. M. Peterson & Streng) based on seed morphology and RFLP analysis of chloroplast non-coding DNA regions.  Ecological Society of America, p. 128
• Ting WT, D Johnson, MN Byappanahalli, RL. Whitman, C Tseng (2005) Genetic diversity of E. coli isolated from Backshore of two freshwater Beaches of Southern Lake Michigan. ASM General Meeting, Paper number Q326

Invited Talks

• A New Genome Scan Technology for E. coli Source Tracking. To be presented at National Beach Conference, Buffalo, New York, to be in Oct. 2006
• Development of DGS (ditag genome scan technology) for detecting E. coli genomic variations.  University of Michigan, March 2006.
• The dynamic changes in DNA repair gene expression in Jurkat cells in response to nanoelectric pulses. Cell Biology Conference December 2005-Special session on Nanosecond Electric Pulses: A New Technology for Introducing Transient nanopores in organelle membranes and trigger apoptosis, San Francisco, CA, December, 2005
• RF effects on human gene expression. Purdue University Calumet, Feb 2005
• Research Activities in the Purdue Consortium. MURI Meeting at ElectroMed2005, Portland, Oregon,  June 2005
• Genomic responses to RF fields: Current research of AFOSR Purdue MURI Consortium. BEMS Dublin, Ireland, July 2005.